non-ESBL-producing E.coli

Non-ESBL/AmpC-producing Escherichia coli. Carbapenemase negative.

The treatment of non-ESBL/AmpC-producing Escherichia coli infections depends on the site of infection, antibiotic susceptibility, and patient factors (such as allergies, renal function, and comorbidities). Since these strains do not produce Extended-Spectrum Beta-Lactamases (ESBLs) or AmpC enyzmes, they are usually susceptible to a broader range of antibiotics including penicillins (ampicillin, amoxicillin/clavulanate) and cephalosporins (first, second and third generation).

Conclusion:
Non-ESBL/AmpC E. coli infections are usually susceptible to beta-lactams (in this case ampicillin resistant), fluoroquinolones, TMP-SMX (in this case resistant), nitrofurantoin, and fosfomycin, depending on infection severity and location.

AMP Ampicillin AMC Amoxicillin/Clavulanate CXM Cefuroxime SXT Trimethoprim-Sulfamethoxazole
CIP Ciprofloxacin FOS Fosfomycin NFE Nitrofurantoin